Basic Information
ID: ALA4673782
Type: Binding
Description: Zinc chelating activity mediated inhibition of Clostridium botulinum BoNT/A1 LC (1 to 425 residues) activity using SNAPtide as substrate incubated with enzyme for 30 mins followed by substrate addition and measured for 20 mins by FRET assay relative to control
Organism: Clostridium botulinum
Activity Charts
Bioactivity
Activity Types for Assay ALA4673782
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 343.40 | 5.23 | 5.23 |
| 351.43 | 4.68 | 4.68 |
| 325.41 | 5.09 | 5.09 |
| 341.86 | 5.60 | 5.60 |
| 310.22 | 4.04 | 4.04 |
| 245.35 | 3.59 | 3.59 |
| 314.24 | 4.78 | 4.78 |
| 300.21 | 4.59 | 4.59 |
| 289.44 | 4.45 | 4.45 |
| 279.79 | 4.13 | 4.13 |
| 259.37 | 3.78 | 3.78 |
| 273.40 | 4.09 | 4.09 |
| 273.40 | 4.09 | 4.09 |
| 265.76 | 3.93 | 3.93 |
| 276.32 | 3.19 | 3.19 |
| 303.47 | 4.84 | 4.84 |
| 321.44 | 5.14 | 5.14 |
| 247.32 | 2.99 | 2.99 |
| 261.35 | 3.29 | 3.29 |