Basic Information
ID: ALA4673830
Type: Binding
Description: Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by PPiLight detection reagent based luminescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: 7,8-dihydro-8-oxoguanine triphosphatase(ALA3708265)
Document: ALA4673201
Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by PPiLight detection reagent based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4673830
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 240.31 | 2.82 | 2.82 |
| 314.39 | 2.47 | 2.47 |
| 315.33 | 0.78 | 0.78 |
| 375.79 | 3.89 | 3.89 |
| 450.35 | 5.04 | 5.04 |
| 295.17 | 3.61 | 3.61 |
| 357.37 | 1.00 | 1.00 |
| 337.38 | 3.36 | 3.36 |
| 384.40 | 0.44 | 0.44 |
| 384.40 | 0.44 | 0.44 |
| 355.40 | 2.15 | 2.15 |
| 329.76 | 4.13 | 4.13 |
| 403.84 | 4.49 | 4.49 |
| 370.37 | 0.10 | 0.10 |
| 279.70 | 2.98 | 2.98 |
| 338.36 | 3.40 | 3.40 |
| 329.36 | 1.23 | 1.23 |
| 235.29 | 3.34 | 3.34 |
| 443.53 | 2.94 | 2.94 |
| 435.53 | 2.93 | 2.93 |
| 249.32 | 3.36 | 3.36 |
| 389.81 | 4.15 | 4.15 |
| 341.37 | 1.76 | 1.76 |
| 370.37 | 0.10 | 0.10 |
| 221.26 | 2.88 | 2.88 |
| 292.39 | 2.98 | 2.98 |