Induction of DNA damage in human IMR-90 cells assessed as increase in p53 phosphorylation at Ser15 at 12 uM measured after 72 hrs by DAPI staining bas...

Basic Information

ID: ALA4674755

Type: ADME

Description: Induction of DNA damage in human IMR-90 cells assessed as increase in p53 phosphorylation at Ser15 at 12 uM measured after 72 hrs by DAPI staining based immunofluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: IMR-90

Target: IMR-90(ALA612577)

Document: ALA4673217

Induction of DNA damage in human IMR-90 cells assessed as increase in p53 phosphorylation at Ser15 at 12 uM measured after 72 hrs by DAPI staining based immunofluorescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4674755

Activity

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
284.25	3.24	3.24
280.28	3.41	3.41

Parent Molecular Weight

ALogP

Polar Surface Area

284.25

3.24

280.28

3.41

Induction of DNA damage in human IMR-90 cells assessed as increase in p53 phosphorylation at Ser15 at 12 uM measured after 72 hrs by DAPI staining bas...

Basic Information

Activity Charts

Compound Summary