Induction of mutation read through activity at human CFTR G542X mutant premature termination codon UGA transfected in FRT cells assessed as increase i...

Basic Information

ID: ALA4674767

Type: Binding

Description: Induction of mutation read through activity at human CFTR G542X mutant premature termination codon UGA transfected in FRT cells assessed as increase in CFTR protein expression at 12 uM incubated for 24 hrs by DAPI-staining based immunofluorescence microscopic analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: FRT

Target:  Unchecked(ALA612545)

Document:  ALA4673217

Induction of mutation read through activity at human CFTR G542X mutant premature termination codon UGA transfected in FRT cells assessed as increase in CFTR protein expression at 12 uM incubated for 24 hrs by DAPI-staining based immunofluorescence microscopic analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
280.283.413.41