ID: ALA4675812
Type: ADME
Description: Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using 5FAM-KKSRGDYMTMQID as substrate in presence of ATP at Km by microfluidic assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4675812
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
383.42 | 2.54 | 2.54 |
387.45 | 1.94 | 1.94 |
383.42 | 2.54 | 2.54 |
369.39 | 2.53 | 2.53 |
398.43 | 1.44 | 1.44 |
369.39 | 2.53 | 2.53 |
383.42 | 2.54 | 2.54 |
388.44 | 2.41 | 2.41 |
401.43 | 1.46 | 1.46 |
413.49 | 2.33 | 2.33 |
388.44 | 2.41 | 2.41 |
383.42 | 2.54 | 2.54 |
441.42 | 2.48 | 2.48 |
397.45 | 2.93 | 2.93 |
397.45 | 2.93 | 2.93 |
369.39 | 2.53 | 2.53 |
403.45 | 0.91 | 0.91 |
369.39 | 2.53 | 2.53 |