Basic Information
ID: ALA4675819
Type: Binding
Description: Inhibition of JAK1/TYK2 signaling pathway in human whole blood assessed as reduction in IL-12 induced STAT4 phosphorylation preincubated for 45 mins followed by IL-12 addition and measured measured after 15 mins by immunostaining based FACS assay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4675819
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.42 | 2.54 | 2.54 |
| 383.42 | 2.54 | 2.54 |
| 369.39 | 2.53 | 2.53 |
| 383.42 | 2.54 | 2.54 |
| 388.44 | 2.41 | 2.41 |