Basic Information
ID: ALA4675821
Type: Unassigned
Description: Selectivity ratio of IC50 for inhibition of JAK2 homodimer signaling pathway in human whole blood spiked with CD34 +ve cells assessed as reduction in EPO induced STAT5 phosphorylation to IC80 for inhibition of JAK2 homodimer signaling pathway in human whole blood spiked with CD34 +ve cells assessed as reduction in EPO induced STAT5 phosphorylation
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4675821
Selectivity ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.42 | 2.54 | 2.54 |
| 383.42 | 2.54 | 2.54 |
| 369.39 | 2.53 | 2.53 |
| 383.42 | 2.54 | 2.54 |
| 388.44 | 2.41 | 2.41 |