Basic Information
ID: ALA4675852
Type: ADME
Description: Inhibition of JAK1/JAK2 signaling pathway in human whole blood spiked with CD14 +ve cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation preincubated for 45 mins followed by IFN-gamma addition and measured measured after 15 mins immunostaining based by FACS assay
Organism: Homo sapiens
Cell type: Lymphocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA4675852
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.42 | 2.54 | 2.54 |