Basic Information
ID: ALA4676054
Type: Binding
Description: Inhibition of 10 nM recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate preincubated for 30 mins followed by ATP addition and measured for 30 mins by pyruvate kinase-lactate dehydrogenase coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4676054
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.35 | 0.47 | 0.47 |
| 396.37 | 1.70 | 1.70 |
| 368.36 | 1.22 | 1.22 |
| 372.35 | 0.47 | 0.47 |
| 382.34 | 1.31 | 1.31 |
| 358.32 | 0.08 | 0.08 |