Basic Information
ID: ALA4676181
Type: Binding
Description: Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followed by LHRH addition and measured after 60 mins by TR-FRET assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4676181
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 672.12 | 5.26 | 5.26 |
| 528.05 | 4.63 | 4.63 |
| 552.10 | 4.75 | 4.75 |
| 499.03 | 5.15 | 5.15 |
| 596.12 | 5.44 | 5.44 |
| 523.66 | 5.23 | 5.23 |
| 614.11 | 5.42 | 5.42 |
| 637.68 | 4.60 | 4.60 |
| 565.64 | 5.08 | 5.08 |
| 555.65 | 3.91 | 3.91 |
| 582.12 | 4.76 | 4.76 |
| 554.67 | 4.54 | 4.54 |
| 534.03 | 5.34 | 5.34 |
| 622.12 | 4.38 | 4.38 |
| 520.05 | 5.70 | 5.70 |
| 620.09 | 5.77 | 5.77 |
| 490.03 | 3.32 | 3.32 |
| 604.13 | 4.24 | 4.24 |
| 589.61 | 5.57 | 5.57 |
| 622.16 | 5.77 | 5.77 |
| 596.12 | 5.28 | 5.28 |
| 539.65 | 4.24 | 4.24 |
| 548.64 | 4.34 | 4.34 |
| 570.09 | 4.89 | 4.89 |
| 672.12 | 5.26 | 5.26 |
| 571.07 | 4.28 | 4.28 |
| 556.06 | 4.50 | 4.50 |
| 561.68 | 4.62 | 4.62 |
| 469.01 | 5.15 | 5.15 |
| 521.61 | 4.63 | 4.63 |
| 569.68 | 3.58 | 3.58 |
| 481.55 | 4.12 | 4.12 |
| 622.16 | 5.77 | 5.77 |
| 600.11 | 4.25 | 4.25 |
| 470.98 | 4.42 | 4.42 |
| 553.08 | 4.14 | 4.14 |
| 655.67 | 4.74 | 4.74 |