Basic Information
ID: ALA4676480
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate to IC50 for inhibition of human coagulation factor XIIA using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate incubated for 1 hr by fluorometric assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4673255
Selectivity index, ratio of IC50 for inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate to IC50 for inhibition of human coagulation factor XIIA using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate incubated for 1 hr by fluorometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4676480
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.30 | 2.11 | 2.11 |
| 384.40 | 2.86 | 2.86 |
| 315.34 | 2.76 | 2.76 |
| 281.28 | 2.48 | 2.48 |
| 405.20 | 2.41 | 2.41 |