Basic Information
ID: ALA4676490
Type: Binding
Description: Inhibition of human coagulation factor XIIA in presence of Boc-Gln-Gly-Arg-AMC as fluorogenic substrate at 1 uM measured at 1 min interval for 1 hr by fluorometric assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Coagulation factor XII(ALA2821)
Document: ALA4673255
Inhibition of human coagulation factor XIIA in presence of Boc-Gln-Gly-Arg-AMC as fluorogenic substrate at 1 uM measured at 1 min interval for 1 hr by fluorometric assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4676490
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.52 | 2.99 | 2.99 |
| 435.89 | 2.52 | 2.52 |
| 279.30 | 1.81 | 1.81 |
| 322.33 | 0.99 | 0.99 |
| 265.28 | 2.12 | 2.12 |
| 376.30 | 2.11 | 2.11 |
| 266.26 | 1.01 | 1.01 |
| 293.33 | 2.17 | 2.17 |
| 315.34 | 2.76 | 2.76 |
| 283.27 | 1.75 | 1.75 |
| 333.27 | 2.63 | 2.63 |
| 319.37 | 2.68 | 2.68 |
| 384.40 | 2.86 | 2.86 |
| 271.32 | 2.14 | 2.14 |
| 310.27 | 1.52 | 1.52 |
| 273.30 | 0.99 | 0.99 |
| 255.24 | 1.20 | 1.20 |
| 315.34 | 2.76 | 2.76 |
| 293.33 | 2.23 | 2.23 |
| 344.17 | 2.37 | 2.37 |
| 279.30 | 1.92 | 1.92 |
| 405.20 | 2.41 | 2.41 |
| 295.30 | 1.62 | 1.62 |
| 310.27 | 1.52 | 1.52 |
| 291.31 | 2.28 | 2.28 |