Basic Information
ID: ALA4676728
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells to IC50 for inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4673259
Selectivity index, ratio of IC50 for inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells to IC50 for inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4676728
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.47 | 2.35 | 2.35 |
| 323.37 | 2.98 | 2.98 |
| 380.36 | 2.63 | 2.63 |
| 397.48 | 3.16 | 3.16 |