Toxicity against SCID/nude mouse xenografted with human SK-ES-1 cells harboring EWSF1 translocation assessed as body weight loss at 0.15 mg/kg, po bid...

Basic Information

ID: ALA4676730

Type: Toxicity

Description: Toxicity against SCID/nude mouse xenografted with human SK-ES-1 cells harboring EWSF1 translocation assessed as body weight loss at 0.15 mg/kg, po bid for 12 days co-administered with 35 mg/kg, po TMZ

Format: BAO_0000218

Organism: Mus musculus

Target:  ADMET(ALA612558)

Document:  ALA4673259

Toxicity against SCID/nude mouse xenografted with human SK-ES-1 cells harboring EWSF1 translocation assessed as body weight loss at 0.15 mg/kg, po bid for 12 days co-administered with 35 mg/kg, po TMZ: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
380.362.632.63
397.483.163.16