Basic Information
ID: ALA4677121
Type: Functional
Description: Antagonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Galpha15 assessed as inhibition of acetylcholine-induced calcium mobilization relative to acetylcholine
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Muscarinic acetylcholine receptor M2(ALA211)
Document: ALA4673268
Antagonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Galpha15 assessed as inhibition of acetylcholine-induced calcium mobilization relative to acetylcholine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4677121
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.39 | 3.28 | 3.28 |
| 286.42 | 3.09 | 3.09 |
| 244.34 | 2.06 | 2.06 |
| 274.36 | 1.69 | 1.69 |
| 287.39 | 2.92 | 2.92 |
| 286.42 | 3.23 | 3.23 |
| 333.44 | 3.96 | 3.96 |
| 258.37 | 2.45 | 2.45 |
| 274.36 | 1.42 | 1.42 |
| 314.82 | 4.12 | 4.12 |
| 272.39 | 2.89 | 2.89 |
| 245.33 | 1.46 | 1.46 |
| 288.39 | 1.81 | 1.81 |
| 282.35 | 2.26 | 2.26 |
| 323.23 | 2.82 | 2.82 |
| 302.42 | 2.06 | 2.06 |
| 244.34 | 2.06 | 2.06 |
| 288.39 | 1.81 | 1.81 |
| 300.45 | 3.62 | 3.62 |
| 335.45 | 4.24 | 4.24 |
| 393.49 | 3.99 | 3.99 |
| 288.39 | 1.81 | 1.81 |
| 300.45 | 3.62 | 3.62 |
| 286.42 | 3.28 | 3.28 |
| 272.39 | 2.84 | 2.84 |
| 274.36 | 2.16 | 2.16 |
| 258.36 | 2.45 | 2.45 |
| 331.42 | 4.02 | 4.02 |
| 302.37 | 1.90 | 1.90 |
| 302.42 | 2.20 | 2.20 |
| 314.36 | 3.31 | 3.31 |
| 258.37 | 2.45 | 2.45 |
| 330.43 | 4.62 | 4.62 |
| 244.34 | 2.06 | 2.06 |
| 284.36 | 2.74 | 2.74 |
| 259.35 | 1.85 | 1.85 |
| 272.39 | 2.76 | 2.76 |
| 284.36 | 2.20 | 2.20 |
| 280.37 | 3.47 | 3.47 |
| 286.42 | 3.09 | 3.09 |
| 288.39 | 1.81 | 1.81 |
| 248.30 | 1.81 | 1.81 |
| 258.37 | 2.45 | 2.45 |
| 300.43 | 3.21 | 3.21 |
| 306.41 | 4.31 | 4.31 |