Basic Information
ID: ALA4677188
Type: Binding
Description: Inhibition of C-terminal TQ5WS-labelled QWAREIGAQLRRMADDLNAQY binding to human C-terminal Cy5-labelled Mcl-1 V321C/C286S mutant (171 to 321 residue) incubated for 2 hrs by fluorescence polarization analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4677188
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 829.27 | 7.76 | 7.76 |
| 595.17 | 5.58 | 5.58 |
| 836.35 | 7.85 | 7.85 |
| 649.24 | 6.75 | 6.75 |
| 789.29 | 6.80 | 6.80 |
| 854.40 | 7.03 | 7.03 |
| 742.09 | 7.05 | 7.05 |
| 771.31 | 7.14 | 7.14 |
| 789.33 | 7.78 | 7.78 |
| 691.23 | 6.84 | 6.84 |
| 890.44 | 8.58 | 8.58 |
| 663.20 | 6.29 | 6.29 |
| 681.19 | 6.43 | 6.43 |
| 644.20 | 6.08 | 6.08 |
| 846.38 | 8.26 | 8.26 |
| 697.64 | 6.94 | 6.94 |
| 775.30 | 7.22 | 7.22 |
| 661.20 | 6.83 | 6.83 |
| 859.42 | 9.17 | 9.17 |
| 759.22 | 7.77 | 7.77 |
| 757.36 | 6.97 | 6.97 |
| 683.23 | 7.43 | 7.43 |
| 844.37 | 6.63 | 6.63 |
| 818.40 | 7.47 | 7.47 |
| 707.68 | 7.35 | 7.35 |
| 785.34 | 7.62 | 7.62 |
| 820.34 | 9.19 | 9.19 |
| 663.27 | 7.06 | 7.06 |
| 827.38 | 7.39 | 7.39 |
| 860.41 | 8.57 | 8.57 |
| 768.31 | 7.80 | 7.80 |
| 769.30 | 7.20 | 7.20 |
| 691.23 | 6.84 | 6.84 |
| 635.19 | 5.40 | 5.40 |
| 799.32 | 7.20 | 7.20 |
| 759.26 | 6.79 | 6.79 |
| 813.40 | 8.36 | 8.36 |
| 758.27 | 7.39 | 7.39 |
| 631.20 | 5.78 | 5.78 |
| 605.16 | 5.39 | 5.39 |
| 875.42 | 8.36 | 8.36 |
| 799.37 | 8.18 | 8.18 |
| 621.20 | 6.44 | 6.44 |
| 839.31 | 8.16 | 8.16 |
| 874.44 | 8.90 | 8.90 |
| 835.36 | 8.46 | 8.46 |
| 761.32 | 7.38 | 7.38 |
| 664.25 | 6.45 | 6.45 |
| 674.22 | 6.09 | 6.09 |
| 609.15 | 5.22 | 5.22 |
| 860.41 | 8.57 | 8.57 |
| 813.40 | 8.40 | 8.40 |
| 803.36 | 7.95 | 7.95 |
| 751.28 | 6.98 | 6.98 |
| 643.21 | 6.69 | 6.69 |
| 846.38 | 8.26 | 8.26 |
| 802.37 | 8.03 | 8.03 |
| 691.23 | 6.84 | 6.84 |
| 875.42 | 8.87 | 8.87 |
| 727.21 | 7.11 | 7.11 |
| 761.28 | 6.73 | 6.73 |
| 819.38 | 7.44 | 7.44 |
| 803.36 | 8.00 | 8.00 |
| 846.38 | 8.26 | 8.26 |
| 625.19 | 5.59 | 5.59 |
| 749.18 | 7.36 | 7.36 |
| 633.17 | 6.28 | 6.28 |
| 817.34 | 6.98 | 6.98 |