Basic Information
ID: ALA4677189
Type: Functional
Description: Induction of apoptosis in human AMO1 cells xenografted in CB-17 SCID mouse assessed as increase in cleaved PARP level at 12.5 mg/kg, iv administered as bolus dose measured after 16 hrs by immunodetection analysis relative to control
Organism: Homo sapiens
Cell type: AMO1
Activity Charts
Bioactivity
Activity Types for Assay ALA4677189
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 829.27 | 7.76 | 7.76 |
| 836.35 | 7.85 | 7.85 |
| 854.40 | 7.03 | 7.03 |
| 789.33 | 7.78 | 7.78 |
| 890.44 | 8.58 | 8.58 |
| 846.38 | 8.26 | 8.26 |
| 859.42 | 9.17 | 9.17 |
| 757.36 | 6.97 | 6.97 |
| 844.37 | 6.63 | 6.63 |
| 818.40 | 7.47 | 7.47 |
| 820.34 | 9.19 | 9.19 |
| 827.38 | 7.39 | 7.39 |
| 860.41 | 8.57 | 8.57 |
| 813.40 | 8.36 | 8.36 |
| 875.42 | 8.36 | 8.36 |
| 799.37 | 8.18 | 8.18 |
| 839.31 | 8.16 | 8.16 |
| 874.44 | 8.90 | 8.90 |
| 835.36 | 8.46 | 8.46 |
| 860.41 | 8.57 | 8.57 |
| 803.36 | 7.95 | 7.95 |
| 846.38 | 8.26 | 8.26 |
| 802.37 | 8.03 | 8.03 |
| 875.42 | 8.87 | 8.87 |
| 819.38 | 7.44 | 7.44 |
| 817.34 | 6.98 | 6.98 |