Basic Information
ID: ALA4677366
Type: ADME
Description: Drug metabolism in mouse liver microsomes assessed as UGT-mediated glucuronidation of the demethylated metabolite at 20 uM preincubated for 3 mins followed by NADPH and UDPGA addition and measured after 60 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Unchecked(ALA612545)
Document: ALA4673282
Drug metabolism in mouse liver microsomes assessed as UGT-mediated glucuronidation of the demethylated metabolite at 20 uM preincubated for 3 mins followed by NADPH and UDPGA addition and measured after 60 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4677366
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.35 | 2.18 | 2.18 |