Basic Information
ID: ALA4677423
Type: Binding
Description: Inhibition of human PD-L1 cocultured in PBMC cells assessed as inhibition of PD1/PDL1 interaction mediated increase in IFN-gamma secretion at 1 uM incubated for 72 hrs by ELISA relative to control
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA4677423
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.55 | 4.51 | 4.51 |
| 522.61 | 4.65 | 4.65 |
| 454.95 | 4.47 | 4.47 |
| 536.63 | 4.96 | 4.96 |