Basic Information
ID: ALA4677854
Type: Binding
Description: Positive allosteric modulator activity at human dopamine D1 receptor expressed in CHO-K1 cells assessed as fold change in dopamine EC50 for beta-arrestin2 recruitment at 50 uM incubated for 90 mins by PathHunter assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Dopamine D1 receptor(ALA2056)
Document: ALA4673311
Positive allosteric modulator activity at human dopamine D1 receptor expressed in CHO-K1 cells assessed as fold change in dopamine EC50 for beta-arrestin2 recruitment at 50 uM incubated for 90 mins by PathHunter assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4677854
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.47 | 4.29 | 4.29 |
| 295.34 | 2.43 | 2.43 |
| 413.52 | 4.67 | 4.67 |
| 415.49 | 4.29 | 4.29 |
| 405.89 | 4.55 | 4.55 |
| 401.47 | 3.90 | 3.90 |
| 399.49 | 4.36 | 4.36 |
| 405.89 | 4.55 | 4.55 |
| 435.91 | 4.56 | 4.56 |
| 389.46 | 3.44 | 3.44 |
| 419.91 | 4.94 | 4.94 |
| 385.47 | 4.20 | 4.20 |
| 463.97 | 5.02 | 5.02 |
| 359.43 | 3.44 | 3.44 |
| 399.49 | 4.59 | 4.59 |
| 449.94 | 4.95 | 4.95 |
| 393.87 | 4.09 | 4.09 |
| 393.87 | 4.09 | 4.09 |
| 371.44 | 3.90 | 3.90 |
| 433.94 | 5.01 | 5.01 |
| 419.91 | 4.94 | 4.94 |
| 423.90 | 4.10 | 4.10 |
| 373.46 | 3.74 | 3.74 |
| 343.39 | 3.12 | 3.12 |
| 433.94 | 5.01 | 5.01 |