Basic Information
ID: ALA4677855
Type: Functional
Description: Positive allosteric modulator activity at human dopamine D1 receptor expressed in HEK293 cells assessed as fold change in dopamine EC50 for cAMP accumulation at 50 uM measured after 30 mins by HitHunter assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4677855
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.47 | 4.29 | 4.29 |
| 295.34 | 2.43 | 2.43 |
| 413.52 | 4.67 | 4.67 |
| 415.49 | 4.29 | 4.29 |
| 405.89 | 4.55 | 4.55 |
| 401.47 | 3.90 | 3.90 |
| 399.49 | 4.36 | 4.36 |
| 405.89 | 4.55 | 4.55 |
| 435.91 | 4.56 | 4.56 |
| 389.46 | 3.44 | 3.44 |
| 419.91 | 4.94 | 4.94 |
| 385.47 | 4.20 | 4.20 |
| 463.97 | 5.02 | 5.02 |
| 359.43 | 3.44 | 3.44 |
| 399.49 | 4.59 | 4.59 |
| 449.94 | 4.95 | 4.95 |
| 393.87 | 4.09 | 4.09 |
| 393.87 | 4.09 | 4.09 |
| 371.44 | 3.90 | 3.90 |
| 433.94 | 5.01 | 5.01 |
| 419.91 | 4.94 | 4.94 |
| 423.90 | 4.10 | 4.10 |
| 373.46 | 3.74 | 3.74 |
| 343.39 | 3.12 | 3.12 |
| 433.94 | 5.01 | 5.01 |