Basic Information
ID: ALA4677855
Type: Functional
Description: Positive allosteric modulator activity at human dopamine D1 receptor expressed in HEK293 cells assessed as fold change in dopamine EC50 for cAMP accumulation at 50 uM measured after 30 mins by HitHunter assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Dopamine D1 receptor(ALA2056)
Document: ALA4673311
Positive allosteric modulator activity at human dopamine D1 receptor expressed in HEK293 cells assessed as fold change in dopamine EC50 for cAMP accumulation at 50 uM measured after 30 mins by HitHunter assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4677855
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.47 | 4.29 | 4.29 |
| 295.34 | 2.43 | 2.43 |
| 413.52 | 4.67 | 4.67 |
| 415.49 | 4.29 | 4.29 |
| 405.89 | 4.55 | 4.55 |
| 401.47 | 3.90 | 3.90 |
| 399.49 | 4.36 | 4.36 |
| 405.89 | 4.55 | 4.55 |
| 435.91 | 4.56 | 4.56 |
| 389.46 | 3.44 | 3.44 |
| 419.91 | 4.94 | 4.94 |
| 385.47 | 4.20 | 4.20 |
| 463.97 | 5.02 | 5.02 |
| 359.43 | 3.44 | 3.44 |
| 399.49 | 4.59 | 4.59 |
| 449.94 | 4.95 | 4.95 |
| 393.87 | 4.09 | 4.09 |
| 393.87 | 4.09 | 4.09 |
| 371.44 | 3.90 | 3.90 |
| 433.94 | 5.01 | 5.01 |
| 419.91 | 4.94 | 4.94 |
| 423.90 | 4.10 | 4.10 |
| 373.46 | 3.74 | 3.74 |
| 343.39 | 3.12 | 3.12 |
| 433.94 | 5.01 | 5.01 |