Basic Information
ID: ALA4677872
Type: Binding
Description: Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by substrate addition by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Proteasome Macropain subunit MB1(ALA4662)
Document: ALA4673312
Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by substrate addition by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4677872
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 719.92 | 2.58 | 2.58 |
| 735.30 | 5.34 | 5.34 |
| 718.30 | 4.45 | 4.45 |
| 735.30 | 5.34 | 5.34 |
| 753.34 | 6.32 | 6.32 |
| 742.32 | 2.91 | 2.91 |
| 718.30 | 4.59 | 4.59 |
| 733.31 | 4.24 | 4.24 |
| 741.33 | 3.51 | 3.51 |
| 732.33 | 4.84 | 4.84 |
| 742.32 | 2.76 | 2.76 |
| 751.35 | 4.15 | 4.15 |
| 717.31 | 5.20 | 5.20 |
| 719.29 | 3.85 | 3.85 |
| 742.32 | 5.07 | 5.07 |
| 735.30 | 5.34 | 5.34 |
| 750.37 | 4.75 | 4.75 |
| 754.33 | 5.71 | 5.71 |
| 747.34 | 5.21 | 5.21 |
| 719.29 | 3.99 | 3.99 |
| 741.33 | 3.37 | 3.37 |