Assay Report Card

Basic Information

ID: ALA4678444

Type: Functional

Description: Potentiation of TMZ-induced antitumor activity against human NCI-H209 cells xenografted in BALB/c nude mouse assessed as inhibition of tumor growth at 0.75 mg/kg, po BID for 28 days and co-treated with 50 mg/kg, po QD TMZ for 5 consecutive days at start of study and again 14 days later

Organism: Homo sapiens

Cell type: NCI-H209

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
298.322.082.08