Basic Information
ID: ALA4678893
Type: Binding
Description: Inhibition of human recombinant N-terminal GST-TEV tagged CDK12 (696 to 1082 residues)/full length human CyclinK expressed in baculovirus expression system using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by MgCl2 addition and measured after 240 mins in presence of 5 mM ATP by mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4678893
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.95 | 3.81 | 3.81 |
| 413.50 | 3.30 | 3.30 |
| 415.93 | 3.57 | 3.57 |