Basic Information
ID: ALA4678924
Type: Binding
Description: Inhibition of recombinant full length human N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged CyclinT1 (1 to 726 residues) expressed in baculovirus infected insect cells using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by MgCl2 addition and measured after 90 mins in presence of 5 mM ATP by mobility shift assay
Format: BAO_0000219
Organism: Homo sapiens
Target: CDK9/cyclin T1(ALA2111389)
Document: ALA4673352
Inhibition of recombinant full length human N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged CyclinT1 (1 to 726 residues) expressed in baculovirus infected insect cells using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by MgCl2 addition and measured after 90 mins in presence of 5 mM ATP by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4678924
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.44 | 3.53 | 3.53 |
| 429.95 | 3.81 | 3.81 |
| 360.85 | 2.89 | 2.89 |
| 395.51 | 3.16 | 3.16 |
| 445.95 | 3.31 | 3.31 |
| 429.95 | 3.81 | 3.81 |
| 431.92 | 3.06 | 3.06 |
| 416.91 | 3.05 | 3.05 |
| 399.47 | 3.05 | 3.05 |
| 427.52 | 3.69 | 3.69 |
| 409.53 | 3.47 | 3.47 |
| 415.93 | 3.42 | 3.42 |
| 413.50 | 3.30 | 3.30 |
| 415.93 | 3.57 | 3.57 |
| 401.90 | 3.18 | 3.18 |
| 389.89 | 3.08 | 3.08 |
| 411.89 | 3.68 | 3.68 |
| 429.95 | 3.81 | 3.81 |
| 383.50 | 3.47 | 3.47 |
| 430.94 | 2.68 | 2.68 |
| 412.88 | 3.08 | 3.08 |
| 411.89 | 3.68 | 3.68 |
| 433.94 | 3.07 | 3.07 |
| 381.48 | 2.91 | 2.91 |
| 415.93 | 3.42 | 3.42 |
| 420.52 | 3.03 | 3.03 |
| 409.53 | 3.55 | 3.55 |
| 429.95 | 3.96 | 3.96 |
| 417.90 | 2.76 | 2.76 |
| 401.90 | 3.18 | 3.18 |
| 415.93 | 3.57 | 3.57 |
| 447.97 | 3.32 | 3.32 |
| 417.90 | 3.01 | 3.01 |
| 429.95 | 3.81 | 3.81 |
| 389.89 | 3.08 | 3.08 |