Basic Information
ID: ALA4678925
Type: Binding
Description: Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA Polymerase 2 CTD phosphorylation at Ser2 residues measured after 6 hrs by immunofluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MCF7
Target: Cyclin-dependent kinase 9(ALA3116)
Document: ALA4673352
Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA Polymerase 2 CTD phosphorylation at Ser2 residues measured after 6 hrs by immunofluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4678925
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.44 | 3.53 | 3.53 |
| 429.95 | 3.81 | 3.81 |
| 360.85 | 2.89 | 2.89 |
| 395.51 | 3.16 | 3.16 |
| 445.95 | 3.31 | 3.31 |
| 429.95 | 3.81 | 3.81 |
| 431.92 | 3.06 | 3.06 |
| 416.91 | 3.05 | 3.05 |
| 399.47 | 3.05 | 3.05 |
| 427.52 | 3.69 | 3.69 |
| 409.53 | 3.47 | 3.47 |
| 415.93 | 3.42 | 3.42 |
| 413.50 | 3.30 | 3.30 |
| 415.93 | 3.57 | 3.57 |
| 401.90 | 3.18 | 3.18 |
| 389.89 | 3.08 | 3.08 |
| 411.89 | 3.68 | 3.68 |
| 429.95 | 3.81 | 3.81 |
| 383.50 | 3.47 | 3.47 |
| 430.94 | 2.68 | 2.68 |
| 412.88 | 3.08 | 3.08 |
| 411.89 | 3.68 | 3.68 |
| 433.94 | 3.07 | 3.07 |
| 381.48 | 2.91 | 2.91 |
| 415.93 | 3.42 | 3.42 |
| 420.52 | 3.03 | 3.03 |
| 409.53 | 3.55 | 3.55 |
| 429.95 | 3.96 | 3.96 |
| 417.90 | 2.76 | 2.76 |
| 401.90 | 3.18 | 3.18 |
| 415.93 | 3.57 | 3.57 |
| 447.97 | 3.32 | 3.32 |
| 417.90 | 3.01 | 3.01 |
| 429.95 | 3.81 | 3.81 |
| 389.89 | 3.08 | 3.08 |