Basic Information
ID: ALA4679433
Type: Binding
Description: Inhibition of human liver mitochondrial KMO at by measuring the 3-HK metabolite formation at 100 nM using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis relative to control
Format: BAO_0000252
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Mitochondria
Target: Kynurenine 3-monooxygenase(ALA2145)
Document: ALA4673377
Inhibition of human liver mitochondrial KMO at by measuring the 3-HK metabolite formation at 100 nM using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4679433
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.44 | 3.80 | 3.80 |