Assay Report Card

Basic Information

ID: ALA4679435

Type: Binding

Description: Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation at 100 nM using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis relative to control

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Mitochondria

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
346.802.992.99
346.802.992.99