ID: ALA4679435
Type: Binding
Description: Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation at 100 nM using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis relative to control
Format: BAO_0000252
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Mitochondria
Target: Kynurenine 3-monooxygenase(ALA3407318)
Document: ALA4673377
Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation at 100 nM using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis relative to control: 1
Bioactivity
Activity Types for Assay ALA4679435
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
346.80 | 2.99 | 2.99 |
346.80 | 2.99 | 2.99 |