Basic Information
ID: ALA4679473
Type: Binding
Description: Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by quanti-blue based SEAP reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-Blue hTLR7
Target: Toll-like receptor 7(ALA5936)
Document: ALA4673381
Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by quanti-blue based SEAP reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4679473
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 439.57 | 2.55 | 2.55 |
| 514.65 | 2.42 | 2.42 |
| 509.68 | 3.14 | 3.14 |
| 438.58 | 3.15 | 3.15 |
| 513.67 | 2.37 | 2.37 |
| 439.57 | 2.55 | 2.55 |