Basic Information
ID: ALA4679477
Type: Binding
Description: Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expression system using PEP as substrate incubated for 17 mins in presence of ATP by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK9/cyclin T1(ALA2111389)
Document: ALA4673382
Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expression system using PEP as substrate incubated for 17 mins in presence of ATP by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4679477
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.61 | 4.35 | 4.35 |
| 461.57 | 2.06 | 2.06 |
| 445.57 | 3.14 | 3.14 |
| 449.53 | 2.93 | 2.93 |
| 493.59 | 2.64 | 2.64 |
| 460.58 | 3.55 | 3.55 |
| 465.58 | 2.67 | 2.67 |
| 479.56 | 2.20 | 2.20 |
| 462.60 | 4.16 | 4.16 |
| 489.62 | 2.84 | 2.84 |
| 467.55 | 4.24 | 4.24 |
| 546.70 | 3.74 | 3.74 |