Basic Information
ID: ALA4679698
Type: Binding
Description: Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at Ser473 residue
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: PI3-kinase p110-gamma subunit(ALA3267)
Document: ALA4673392
Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at Ser473 residue: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4679698
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.39 | 2.01 | 2.01 |
| 370.48 | 3.18 | 3.18 |
| 384.51 | 3.57 | 3.57 |
| 344.44 | 2.79 | 2.79 |
| 370.48 | 3.18 | 3.18 |
| 407.50 | 3.34 | 3.34 |
| 406.51 | 3.95 | 3.95 |
| 386.52 | 3.82 | 3.82 |
| 398.53 | 3.80 | 3.80 |
| 330.41 | 2.40 | 2.40 |
| 416.50 | 2.81 | 2.81 |
| 416.46 | 3.07 | 3.07 |
| 395.49 | 3.28 | 3.28 |
| 400.50 | 3.19 | 3.19 |
| 386.48 | 2.80 | 2.80 |
| 406.51 | 3.95 | 3.95 |
| 395.49 | 3.05 | 3.05 |
| 424.45 | 3.81 | 3.81 |
| 356.45 | 2.79 | 2.79 |
| 384.51 | 3.49 | 3.49 |
| 417.49 | 2.21 | 2.21 |
| 386.48 | 2.80 | 2.80 |
| 408.49 | 2.74 | 2.74 |
| 416.46 | 3.07 | 3.07 |
| 412.90 | 4.10 | 4.10 |
| 374.44 | 2.93 | 2.93 |