Basic Information
ID: ALA4679815
Type: Functional
Description: Antagonist activity at human recombinant muscarinic receptor M1 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubated for 30 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Muscarinic acetylcholine receptor M1(ALA216)
Document: ALA4673395
Antagonist activity at human recombinant muscarinic receptor M1 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubated for 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4679815
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.51 | 1.65 | 1.65 |
| 406.51 | 4.14 | 4.14 |
| 407.49 | 3.53 | 3.53 |
| 467.58 | 2.61 | 2.61 |
| 378.45 | 3.44 | 3.44 |
| 390.46 | 3.44 | 3.44 |
| 441.54 | 2.08 | 2.08 |
| 483.58 | 1.84 | 1.84 |
| 406.51 | 4.14 | 4.14 |
| 427.55 | 3.78 | 3.78 |
| 426.92 | 4.48 | 4.48 |
| 406.51 | 4.14 | 4.14 |
| 455.57 | 2.46 | 2.46 |
| 392.48 | 3.75 | 3.75 |
| 406.51 | 4.14 | 4.14 |
| 406.51 | 4.14 | 4.14 |
| 450.97 | 2.86 | 2.86 |
| 465.00 | 3.17 | 3.17 |
| 385.47 | 3.17 | 3.17 |
| 476.60 | 3.43 | 3.43 |
| 441.54 | 2.08 | 2.08 |
| 407.49 | 3.53 | 3.53 |
| 469.59 | 2.85 | 2.85 |
| 392.48 | 3.83 | 3.83 |
| 385.47 | 3.17 | 3.17 |
| 408.93 | 4.34 | 4.34 |
| 390.46 | 3.58 | 3.58 |
| 469.59 | 2.85 | 2.85 |
| 390.49 | 3.31 | 3.31 |
| 434.52 | 2.34 | 2.34 |
| 440.55 | 3.13 | 3.13 |
| 436.53 | 3.63 | 3.63 |
| 413.52 | 2.97 | 2.97 |
| 388.51 | 4.00 | 4.00 |
| 467.58 | 2.61 | 2.61 |
| 360.46 | 3.30 | 3.30 |
| 378.45 | 3.44 | 3.44 |
| 396.47 | 3.73 | 3.73 |
| 467.58 | 2.61 | 2.61 |
| 430.56 | 2.51 | 2.51 |
| 392.48 | 3.83 | 3.83 |
| 469.59 | 2.85 | 2.85 |
| 484.52 | 3.22 | 3.22 |
| 484.52 | 3.22 | 3.22 |
| 412.53 | 4.20 | 4.20 |
| 462.57 | 3.04 | 3.04 |
| 455.57 | 2.46 | 2.46 |
| 469.59 | 2.85 | 2.85 |
| 438.53 | 3.04 | 3.04 |
| 414.51 | 3.39 | 3.39 |