Basic Information
ID: ALA4679832
Type: Binding
Description: Inhibition of recombinant full length wild-type phosphorylated CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in production of ADP using 5-FAM-QSPKKG-CONH2 peptide as substrate preincubated with enzyme for 15 mins followed by further incubation with ATP for 45 mins by fluorescence-based microfluidic mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Cyclin-dependent kinase 2/cyclin E1(ALA1907605)
Document: ALA4673400
Inhibition of recombinant full length wild-type phosphorylated CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in production of ADP using 5-FAM-QSPKKG-CONH2 peptide as substrate preincubated with enzyme for 15 mins followed by further incubation with ATP for 45 mins by fluorescence-based microfluidic mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4679832
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.53 | 2.04 | 2.04 |
| 460.56 | 1.17 | 1.17 |
| 461.59 | 1.88 | 1.88 |
| 421.52 | 0.96 | 0.96 |
| 485.56 | 1.91 | 1.91 |
| 421.52 | 1.10 | 1.10 |
| 420.54 | 1.77 | 1.77 |
| 443.93 | 2.34 | 2.34 |
| 436.54 | 0.61 | 0.61 |
| 490.61 | 1.99 | 1.99 |
| 425.94 | 2.40 | 2.40 |
| 422.51 | 0.35 | 0.35 |
| 470.98 | 1.26 | 1.26 |
| 478.58 | 0.13 | 0.13 |