Assay Report Card

Basic Information

ID: ALA4679883

Type: Binding

Description: Protac activity at CRBN/HPGDS in human KU812 cells assessed as induction of HPGDS degradation at 10 to 100 nM incubated for 24 hrs followed by compound washout and further incubated for 6 hrs in compound-free medium by Western blot analysis

Organism: Homo sapiens

Cell type: KU812 cell line

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1048.16
1034.14