Assay Report Card

Basic Information

ID: ALA4679886

Type: Binding

Description: Protac activity at CRBN/HPGDS in human KU812 cells assessed as induction of HPGDS degradation at 100 nM measured after 6 hrs in presence of ubiquitin-activating enzyme inhibitor MLN7243 by Western blot analysis

Organism: Homo sapiens

Cell type: KU812 cell line

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1034.14