Assay Report Card

Basic Information

ID: ALA4679893

Type: Binding

Description: Protac activity at CRBN/Cyclin B1 in human KU812 cells assessed as decrease in cyclin B1 protein level by measuring protein turnover at 100 nM measured within 6 hrs in presence of protein synthesis inhibitor cycloheximide by Western blot analysis

Organism: Homo sapiens

Cell type: KU812 cell line

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1034.14