Basic Information
ID: ALA4680567
Type: Binding
Description: Inhibition of recombinant human His-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 as substrate incubated for 8 mins in presence of [3H]-SAM cofactor by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4680567
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 304.35 | 3.18 | 3.18 |
| 304.35 | 3.17 | 3.17 |
| 447.54 | 4.83 | 4.83 |
| 356.43 | 3.30 | 3.30 |
| 343.39 | 3.65 | 3.65 |
| 330.39 | 3.73 | 3.73 |
| 321.34 | 2.25 | 2.25 |
| 344.37 | 3.92 | 3.92 |
| 344.37 | 3.92 | 3.92 |
| 394.48 | 3.52 | 3.52 |
| 343.39 | 3.65 | 3.65 |
| 373.42 | 2.38 | 2.38 |
| 343.39 | 3.65 | 3.65 |
| 372.43 | 2.12 | 2.12 |
| 321.34 | 2.25 | 2.25 |
| 373.42 | 2.38 | 2.38 |
| 396.45 | 4.05 | 4.05 |
| 372.50 | 3.77 | 3.77 |
| 355.45 | 3.04 | 3.04 |
| 368.44 | 4.15 | 4.15 |
| 392.47 | 2.52 | 2.52 |
| 382.42 | 0.25 | 0.25 |
| 395.47 | 3.78 | 3.78 |
| 370.41 | 4.47 | 4.47 |
| 358.40 | 4.31 | 4.31 |
| 369.43 | 3.28 | 3.28 |
| 395.47 | 3.78 | 3.78 |
| 393.49 | 3.52 | 3.52 |
| 345.41 | 3.27 | 3.27 |
| 345.41 | 3.27 | 3.27 |
| 262.28 | 1.89 | 1.89 |
| 360.44 | 4.39 | 4.39 |