Basic Information
ID: ALA4681093
Type: Functional
Description: Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Flp-In-293
Target: Serotonin 2b (5-HT2b) receptor(ALA1833)
Document: ALA4680082
Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4681093
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 195.69 | 2.59 | 2.59 |
| 253.73 | 2.50 | 2.50 |
| 295.81 | 3.46 | 3.46 |
| 281.78 | 2.25 | 2.25 |
| 283.80 | 2.47 | 2.47 |
| 309.84 | 3.85 | 3.85 |
| 281.78 | 3.07 | 3.07 |
| 321.85 | 3.85 | 3.85 |
| 253.73 | 2.50 | 2.50 |
| 283.80 | 2.47 | 2.47 |
| 293.79 | 3.28 | 3.28 |
| 313.80 | 3.41 | 3.41 |
| 287.76 | 2.03 | 2.03 |
| 293.79 | 3.45 | 3.45 |
| 267.76 | 2.89 | 2.89 |
| 287.76 | 2.03 | 2.03 |
| 293.79 | 3.28 | 3.28 |
| 295.81 | 2.47 | 2.47 |
| 281.78 | 3.28 | 3.28 |
| 297.76 | 3.36 | 3.36 |
| 307.82 | 3.62 | 3.62 |
| 313.80 | 3.41 | 3.41 |
| 333.31 | 1.69 | 1.69 |
| 285.75 | 2.84 | 2.84 |
| 279.77 | 3.06 | 3.06 |
| 293.79 | 3.45 | 3.45 |
| 295.81 | 3.46 | 3.46 |
| 281.78 | 3.28 | 3.28 |
| 333.31 | 1.69 | 1.69 |
| 295.81 | 2.47 | 2.47 |
| 285.75 | 2.84 | 2.84 |
| 307.82 | 3.62 | 3.62 |
| 281.78 | 2.25 | 2.25 |
| 281.78 | 3.28 | 3.28 |
| 281.78 | 3.28 | 3.28 |
| 321.85 | 3.85 | 3.85 |
| 281.78 | 3.07 | 3.07 |
| 269.77 | 2.08 | 2.08 |
| 269.77 | 2.08 | 2.08 |
| 279.77 | 3.06 | 3.06 |
| 309.84 | 3.85 | 3.85 |
| 297.76 | 3.36 | 3.36 |
| 267.76 | 2.89 | 2.89 |