Basic Information
ID: ALA4681103
Type: Functional
Description: Agonist activity at human 5-HT2C INI receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux by measuring log (Emax/EC50) incubated for 1 hr by Fluo-4 direct dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Flp-In-293
Target: Serotonin 2c (5-HT2c) receptor(ALA225)
Document: ALA4680082
Agonist activity at human 5-HT2C INI receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux by measuring log (Emax/EC50) incubated for 1 hr by Fluo-4 direct dye based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4681103
log(ratio)
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 195.69 | 2.59 | 2.59 |
| 342.75 | 2.78 | 2.78 |
| 281.78 | 2.25 | 2.25 |
| 287.76 | 2.03 | 2.03 |
| 313.80 | 3.41 | 3.41 |
| 285.75 | 2.84 | 2.84 |
| 307.82 | 3.62 | 3.62 |
| 279.77 | 3.06 | 3.06 |