Basic Information
ID: ALA4681202
Type: Binding
Description: Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay
Organism: Homo sapiens
Cell type: SK-MEL-24
Activity Charts
Bioactivity
Activity Types for Assay ALA4681202
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.61 | 2.95 | 2.95 |
| 708.81 | 2.89 | 2.89 |
| 391.30 | 0.75 | 0.75 |
| 448.35 | -0.13 | -0.13 |
| 377.28 | 0.36 | 0.36 |
| 319.32 | 0.72 | 0.72 |
| 262.26 | 1.60 | 1.60 |
| 262.26 | 0.97 | 0.97 |
| 333.34 | 1.11 | 1.11 |
| 377.28 | 0.16 | 0.16 |
| 462.38 | 0.06 | 0.06 |
| 462.38 | 0.26 | 0.26 |