Basic Information
ID: ALA4681209
Type: Binding
Description: Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4681209
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.61 | 2.95 | 2.95 |
| 708.81 | 2.89 | 2.89 |
| 646.66 | -4.23 | -4.23 |
| 574.64 | -2.52 | -2.52 |
| 601.62 | -5.29 | -5.29 |
| 448.35 | -0.13 | -0.13 |
| 377.28 | 0.36 | 0.36 |
| 248.24 | 1.21 | 1.21 |
| 129.11 | -0.65 | -0.65 |
| 319.32 | 0.72 | 0.72 |
| 262.26 | 1.60 | 1.60 |
| 319.32 | 0.72 | 0.72 |
| 262.26 | 0.97 | 0.97 |
| 333.34 | 1.11 | 1.11 |
| 377.28 | 0.16 | 0.16 |
| 462.38 | 0.06 | 0.06 |
| 391.30 | 0.55 | 0.55 |
| 462.38 | 0.26 | 0.26 |