Basic Information
ID: ALA4681360
Type: Binding
Description: Inhibition of C-terminal His-tagged recombinant human HDAC1 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured after 2 hrs by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Histone deacetylase 1(ALA325)
Document: ALA4680089
Inhibition of C-terminal His-tagged recombinant human HDAC1 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured after 2 hrs by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4681360
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.42 | 2.66 | 2.66 |
| 351.45 | 3.05 | 3.05 |
| 379.50 | 3.83 | 3.83 |
| 323.40 | 2.27 | 2.27 |
| 365.48 | 3.44 | 3.44 |