Basic Information
ID: ALA4681448
Type: Functional
Description: In-vivo inhibition of MDM2 in BomTac:NMRI-Foxn1^nu mouse xenografted with human SJSA-1 cells assessed as induction of cleaved caspse-3 protein accumulation at 100 mg/kg, po administered as single dose and measured after 6 to 24 hrs by mesoscale assay
Format: BAO_0000218
Organism: Mus musculus
Strain: NMRI
Target: Unchecked(ALA612545)
Document: ALA4680091
In-vivo inhibition of MDM2 in BomTac:NMRI-Foxn1^nu mouse xenografted with human SJSA-1 cells assessed as induction of cleaved caspse-3 protein accumulation at 100 mg/kg, po administered as single dose and measured after 6 to 24 hrs by mesoscale assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4681448
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 566.46 | 5.96 | 5.96 |