Assay Report Card

Basic Information

ID: ALA4681669

Type: Binding

Description: Inhibition of catalytic activity of LRS in HEK293 cells assessed as reduction in mTORC1 activation by measuring leucine-induced S6K phosphorylation at 12.5 to 200 uM by immunoblotting analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
459.49-2.22-2.22
586.37-1.58-1.58
476.47-3.22-3.22