Basic Information
ID: ALA4681994
Type: Binding
Description: Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 30 mins before Ser/Thr 07 peptide substrate and 10 uM ATP addition and further incubated for 90 mins by Z'-lyte assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4681994
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.78 | 3.75 | 3.75 |
| 280.76 | 4.65 | 4.65 |
| 296.76 | 3.63 | 3.63 |
| 297.75 | 3.02 | 3.02 |
| 382.85 | 4.89 | 4.89 |
| 324.77 | 4.35 | 4.35 |
| 373.89 | 5.99 | 5.99 |
| 304.35 | 4.00 | 4.00 |
| 322.32 | 2.49 | 2.49 |
| 401.88 | 3.34 | 3.34 |
| 382.85 | 4.89 | 4.89 |
| 324.77 | 4.35 | 4.35 |
| 320.35 | 3.61 | 3.61 |
| 383.83 | 4.29 | 4.29 |
| 364.83 | 4.77 | 4.77 |
| 354.80 | 3.54 | 3.54 |
| 315.33 | 3.57 | 3.57 |
| 368.82 | 4.50 | 4.50 |
| 320.35 | 3.61 | 3.61 |
| 324.77 | 4.35 | 4.35 |
| 308.31 | 3.84 | 3.84 |
| 368.82 | 4.50 | 4.50 |
| 366.85 | 5.01 | 5.01 |
| 338.84 | 5.44 | 5.44 |
| 416.92 | 5.02 | 5.02 |
| 392.89 | 5.55 | 5.55 |
| 354.79 | 4.11 | 4.11 |
| 396.87 | 5.14 | 5.14 |
| 401.88 | 3.48 | 3.48 |
| 366.85 | 5.01 | 5.01 |
| 364.83 | 4.77 | 4.77 |
| 408.89 | 4.78 | 4.78 |
| 408.89 | 5.43 | 5.43 |
| 298.34 | 3.21 | 3.21 |
| 290.32 | 3.70 | 3.70 |
| 358.32 | 4.71 | 4.71 |
| 294.31 | 2.43 | 2.43 |
| 348.80 | 3.83 | 3.83 |
| 352.82 | 4.67 | 4.67 |
| 324.77 | 4.35 | 4.35 |
| 325.76 | 3.74 | 3.74 |
| 320.35 | 3.70 | 3.70 |