Basic Information
ID: ALA4682224
Type: Binding
Description: Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine-protein kinase ATM(ALA3797)
Document: ALA4680114
Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4682224
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.68 | 4.25 | 4.25 |
| 476.60 | 4.28 | 4.28 |
| 520.65 | 4.30 | 4.30 |
| 448.54 | 4.18 | 4.18 |
| 520.65 | 4.30 | 4.30 |
| 477.58 | 4.76 | 4.76 |
| 526.61 | 4.92 | 4.92 |
| 562.69 | 4.07 | 4.07 |
| 465.57 | 4.61 | 4.61 |
| 548.71 | 5.08 | 5.08 |
| 546.69 | 4.83 | 4.83 |
| 546.69 | 4.83 | 4.83 |
| 449.53 | 3.98 | 3.98 |
| 465.57 | 4.61 | 4.61 |
| 548.71 | 5.08 | 5.08 |
| 451.54 | 3.96 | 3.96 |
| 518.64 | 4.05 | 4.05 |
| 476.60 | 4.65 | 4.65 |
| 519.67 | 3.83 | 3.83 |
| 491.61 | 5.00 | 5.00 |
| 451.54 | 4.39 | 4.39 |
| 526.61 | 4.92 | 4.92 |
| 540.63 | 5.31 | 5.31 |
| 477.58 | 4.71 | 4.71 |
| 520.65 | 4.30 | 4.30 |
| 494.59 | 4.23 | 4.23 |
| 546.69 | 4.83 | 4.83 |
| 534.68 | 4.69 | 4.69 |
| 512.58 | 4.53 | 4.53 |
| 476.60 | 4.28 | 4.28 |
| 434.52 | 4.16 | 4.16 |
| 562.73 | 5.06 | 5.06 |
| 393.46 | 3.90 | 3.90 |
| 503.62 | 4.23 | 4.23 |
| 407.49 | 4.21 | 4.21 |
| 548.71 | 5.08 | 5.08 |
| 460.56 | 4.55 | 4.55 |
| 451.54 | 4.39 | 4.39 |
| 532.66 | 4.44 | 4.44 |
| 520.65 | 4.30 | 4.30 |
| 435.55 | 4.94 | 4.94 |