Basic Information
ID: ALA4682295
Type: Functional
Description: Inhibition of ATM in 6 to 12-month-old Q175 neo minus mouse assessed as reduction in KAP1 phosphorylation at 100 mg/kg, po dosed 1 hr before 5 Gy irradiation and measured 60 mins post-irradiation by Western blot analysis
Format: BAO_0000218
Organism: Mus musculus
Target: Unchecked(ALA612545)
Document: ALA4680114
Inhibition of ATM in 6 to 12-month-old Q175 neo minus mouse assessed as reduction in KAP1 phosphorylation at 100 mg/kg, po dosed 1 hr before 5 Gy irradiation and measured 60 mins post-irradiation by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4682295
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.49 | 4.21 | 4.21 |