Basic Information
ID: ALA4682305
Type: Functional
Description: Binding affinity to ATM in wild type mouse assessed as free plasma concentration necessary to achieve 50% occupancy at 100 mg/kg, po dosed 1 hr before 5 Gy irradiation and measured 60 mins post-irradiation by biotin-tagged irreversible ADP probe based target engagement assay
Format: BAO_0000218
Organism: Mus musculus
Target: Unchecked(ALA612545)
Document: ALA4680114
Binding affinity to ATM in wild type mouse assessed as free plasma concentration necessary to achieve 50% occupancy at 100 mg/kg, po dosed 1 hr before 5 Gy irradiation and measured 60 mins post-irradiation by biotin-tagged irreversible ADP probe based target engagement assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4682305
Occ
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.49 | 4.21 | 4.21 |