Basic Information
ID: ALA4682342
Type: Binding
Description: Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular response upto 72 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Dihydroorotate dehydrogenase(ALA1966)
Document: ALA4680118
Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular response upto 72 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4682342
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.36 | 5.85 | 5.85 |
| 270.21 | 3.00 | 3.00 |
| 355.37 | 4.00 | 4.00 |
| 179.17 | 1.19 | 1.19 |
| 219.24 | 2.12 | 2.12 |
| 259.31 | 2.51 | 2.51 |
| 273.33 | 2.90 | 2.90 |
| 261.32 | 2.76 | 2.76 |
| 219.24 | 1.59 | 1.59 |
| 287.36 | 3.29 | 3.29 |
| 245.28 | 2.12 | 2.12 |
| 281.31 | 2.62 | 2.62 |
| 247.29 | 2.37 | 2.37 |
| 249.31 | 1.84 | 1.84 |
| 233.27 | 1.98 | 1.98 |
| 301.39 | 3.68 | 3.68 |
| 233.27 | 1.72 | 1.72 |
| 273.33 | 2.59 | 2.59 |