Basic Information
ID: ALA4682613
Type: Functional
Description: Cytotoxicity against human DU145 cells expressing mutant type p53 assessed as reduction in cell viability preincubated for 48 hrs and measured after 4 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: DU-145
Target: DU-145(ALA613508)
Document: ALA4680124
Cytotoxicity against human DU145 cells expressing mutant type p53 assessed as reduction in cell viability preincubated for 48 hrs and measured after 4 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4682613
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.53 | 0.00 | 0.00 |
| 362.48 | 4.17 | 4.17 |
| 426.95 | 4.83 | 4.83 |
| 452.99 | 5.71 | 5.71 |
| 396.88 | 4.33 | 4.33 |
| 405.50 | 4.85 | 4.85 |
| 452.99 | 5.37 | 5.37 |
| 438.92 | 3.93 | 3.93 |
| 436.94 | 5.08 | 5.08 |
| 406.53 | 4.57 | 4.57 |
| 410.91 | 4.55 | 4.55 |
| 378.48 | 3.97 | 3.97 |
| 434.58 | 5.35 | 5.35 |
| 391.48 | 4.46 | 4.46 |
| 392.50 | 4.18 | 4.18 |
| 425.92 | 5.12 | 5.12 |
| 439.95 | 5.51 | 5.51 |
| 412.92 | 4.44 | 4.44 |
| 440.98 | 5.22 | 5.22 |
| 376.46 | 3.89 | 3.89 |
| 404.47 | 3.27 | 3.27 |
| 397.87 | 4.34 | 4.34 |
| 418.54 | 4.72 | 4.72 |
| 424.93 | 4.94 | 4.94 |
| 418.54 | 5.06 | 5.06 |
| 455.00 | 5.61 | 5.61 |
| 420.51 | 3.56 | 3.56 |
| 390.49 | 4.28 | 4.28 |
| 405.46 | 3.45 | 3.45 |
| 469.03 | 6.00 | 6.00 |
| 397.87 | 4.51 | 4.51 |
| 363.42 | 3.68 | 3.68 |
| 396.88 | 4.16 | 4.16 |
| 363.42 | 3.86 | 3.86 |
| 437.93 | 5.26 | 5.26 |
| 403.49 | 4.61 | 4.61 |
| 453.97 | 5.89 | 5.89 |
| 362.43 | 3.68 | 3.68 |
| 362.43 | 3.50 | 3.50 |
| 420.56 | 4.96 | 4.96 |
| 377.45 | 4.07 | 4.07 |
| 454.96 | 4.21 | 4.21 |
| 404.51 | 4.67 | 4.67 |
| 378.48 | 3.79 | 3.79 |
| 411.89 | 4.73 | 4.73 |
| 439.90 | 4.11 | 4.11 |
| 438.96 | 5.33 | 5.33 |
| 419.53 | 5.24 | 5.24 |
| 412.92 | 4.62 | 4.62 |
| 402.50 | 4.43 | 4.43 |